Core vaccines for dogs include distemper, adenovirus, parvovirus, and rabies. Core vaccines for cats include panleukopenia, calicivirus, herpesvirus, and rabies. Non-core vaccines such as Bordetella, leptospirosis, and feline leukemia are recommended based on lifestyle and exposure risk. Puppies and kittens receive an initial vaccine series starting at six to eight weeks, with boosters every three to four weeks until around sixteen weeks of age. Adult pets receive boosters on a schedule determined by the vaccine type and local regulations. Mild side effects like soreness or low-grade fever are normal; severe reactions are rare but warrant immediate veterinary attention.